Selena Marie Gomez was, for a moment, widely known for her rebellious character on Disney Channel, Alex Russo. Today, she is an A list celebrity whom associates herself with a so called ‘squad’ lead by another A list celeb Taylor Swift. Gomez had a long tumultuous on and off again relationship with YouTube phenomenon turned pop star Justin Bieber. Selena Gomez now has a very successful album and looked past her unfortunate diagnosis with lupus.
Onika Miraj, more famously known for her figure in the Nicki Minaj big ass persona, was born in Trinidad and raised by her mother who also raised Minaj’s brother. Nicki Minaj reported to have an abusive father who once successfully burned her home down in Bronx, New York. Nicki Minaj is now a leading rap star who has delved into pop music. She got her start from being featured onto dozens of other rapper’s songs — some only 30 seconds of her rapping, others at 2:00+ minutes.
There are seldom movies where there are sex scenes where the actors have actually participated in intercourse onscreen. The reasoning for this is — well, the list is never ending. However, there are a select few movies where the actors were actually being filmed onscreen doing the hanky panky. Nymphomanic: Volume I was one of few. This film starred Shia La Beouf who agreed to the raunchy scenes. As it turned out, however, it was performed by two pornographic actors. Additionally, The Brown Bunny is an independent Cannes film where actress Chloë Sevigny gives actor Vincent Gallo a very much real oral pleasure. A lot were skeptical if it was real until Chloë Sevigny herself confirmed it was indeed legitimate.
Avaaz is a political action group that brings change and activism to human rights, corruption, conflict, poverty and climate change. Avaaz was founded in 2007 and they chose their name based on its translation. In most spoken languages it translates to the song or voice. Avaaz wants to be the voice for those who need someone to speak up for them. Recently Avaaz had their lawyers draft documents to the chief of the UK’s Office of Communications. Sky media is a UK based pay for service television provider, they have been trying to maintain their UK broadcasting license but are under the control of Rupert Murdoch. Rupert is a media centered billionaire. Mr. Murdoch is trying to have fox obtain rights to Sky media. He is hoping to purchase the 61% of sky media that fox does not currently own. Avaaz is hoping to reopen the “fit and proper” debate for fox. Recently fox was put under a lot of scrutiny in the United States over sexual and racial harassment allegations. Avaaz and sky media are concerned that the acquisition would give Rupert Murdoch and his family to much control over broadcasting within the United Kingdom. Opponents of the deal also want a review of Fox’s commitment towards meeting broadcasting standards. In addition to the review Avaaz is demanding the minutes from meetings between Murdoch, Fox and Ofcom representatives. Ofcom has always relied heavily on what they have been told and taken it at face value rather than digging deeper into documents. When this acquisition was presented, Ofcom made errors and used Fox reassurance while ignoring important legal evidence despite a history of false statements by Fox representatives.
Born on 16th of July in Jao Pessoa Brazil Roberto Santiago came out feet first and hit the ground running. As a young boy, he was a hard worker in a manufacturing plant. He designed and fabricated cardboard products.
As he got older he made the transition into the real estate world. He developed the reputation of one of Brazil’s most impressive realtors. Mr. Santiago continued to expand his horizons into various different entrepreneur endeavors as well developing himself into a potent writer of novels. Along the way, he has amassed great wealth. He credits all of his success to his hard work and business model.
Pio X-Marist College
University Center of Joao Pessoa: Undergraduate Degree in Business Administration (BA).
Let’s Go Shopping
Roberto Santiago acquired a large area of land and within two years he formulated the Manaira Shopping Mall. A luxurious mega shopping complex with state of the art design and function. The Manaira parent over 250 businesses including:
Arts & Entertainment
They have a beautiful, sleek, and informative website entitled “Viva Maringa” (vivamaringa.odiario.com) that you should visit before visiting the Manaira. A place for everyone families makes a day out of visiting this magnificent shopping structure.
They have a beautiful concert hall that has a total capacity of 14,000 individuals and they frequently host free performances of great artist and shows. They have a gaming area stocked with all of the latest titles as well as classic games.
If you’re hungry their food court has various options to satisfy your pallet from junk food to gourmet. If you’re stress out and need a quick work out to balance out, hit their gym and if you’re short on cash stop by their on the premisies bank. They even have a college for your scholarly needs.
More impressive about Roberto Santiago is his love for Brazil. He has committed to making Brazil a better place for shopping. Mr. Santiago meets the customer’s demands with empathy and swiftness. He has loaded the Maringa with a great staff of highly trained customer service professionals ready to address your needs. Let’s go shopping.
The Food and Drug Administration (FDA) has a pivotal role in the development of new biopharmaceutical products. While the complex regulatory approval process provides an essential public service, the high capital costs and the length of time to complete the process can have an adverse affect to a pharmaceutical company.
Take for example the path that migalastat (marketed as Galafold) and its originator, Amicus Therapeutics Inc. (Amicus Therapeutics), had to endure. Amicus Therapeutics is a publicly held global biotechnology company based in Cranbury, New Jersey. The company has developed many treatments for a range of genetic diseases, but their lead product candidate is migalastat, which is used to treat individuals with Fabry disease, a disorder resulting from abnormal deposits of a particular fatty substance in blood vessel walls throughout the body, causing decreased blood flow and decreased nourishment of the tissues normally supplied by these vessels.
In November 2016, Amicus Therapeutics was counting on the FDA approving Galafold without requiring more information, and clinical studies that would delay the process in light of the fact that the drug was already being marketed in Europe (Crunchbase). The FDA decided that additional studies were needed before the drug is approved, particularly to assess how the drug affects gastrointestinal systems. This decision had the potential to hand Amicus a delay that could last years, causing their share price to tumble.
Amicus Therapeutics opened a dialogue with the FDA regulators and after multiple conversations, the company was successful in making an argument that there was enough current data of the effectiveness of the drug to warrant immediate consideration (https://seekingalpha.com/article/4073303-amicus-therapeutics-small-biotech-seems-big-mo). As a result, the FDA reversed itself and the share price of Amicus Therapeutics spiked. The drug is currently approved in the European Union, Israel, and Switzerland. Recently, Amicus Therapeutics announced that the Australian Therapeutic Goods Administration has approved Galafold for certain patients that have Fabry disease, which is a significant step forward for Amicus Therapeutics and the Fabry community.